Extended Data Fig. 8. Characterization of physiological changes of iWAT after sensory ablation.
a–b, Quantitative RT-PCR analysis of eWAT (a) and iBAT (b) from mice with bilateral sensory ablation of iWAT (n = 4 mice per group). c–h, Physiological measurement of mice with bilateral sensory ablation. c, Rectal temperature at room temperature of Cre- (n = 9) and Cre+ (n = 10). d, Body weight of Cre- (n = 9) and Cre+ (n = 10). e, 24 h food intake of Cre- (n = 11) and Cre+ (n = 13). f–h, Systolic (f), diastolic (g) and mean (h) blood pressure of Cre- (n = 6) and Cre+ (n = 6). i, Bulk iWAT noradrenaline (NA) amount in mice with unilateral sensory ablation (n = 9). j–n, Metabolic measurement of mice with bilateral sensory ablation on high-fat diet (HFD) in thermoneutral temperature. j–k, Body weight (j) and body weight gain (k) of Cre- (n = 5) and Cre+ (n = 6) mice on HFD. l, Fasting glucose levels in Cre- (n = 5) and Cre+ (n = 6) mice after 9 weeks of HFD. m, Fasting plasma insulin levels in Cre- (n = 5) and Cre+ (n = 6) mice after 14 weeks of HFD. n, IP-glucose tolerance test (1 g/kg) in Cre- (n = 5) and Cre+ (n = 6) mice after 9 weeks of HFD. c–h, j–n are shown as mean ± s.e.m. Statistics determined by two-tailed unpaired t test in a–b; two-tailed unpaired t test with Welch’s correction in c–h, l–m; 2-way ANOVA in j, k, n.