Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 15;5:963. doi: 10.1038/s42003-022-03933-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — a Schematic representation of working mechanism of Type II TA system. b Sequence specific assignments are indicated on the 2D ¹H-¹⁵N HSQC spectrum of MazE6. Inset shows the assignment for the crowded region of the spectrum within the box. Assignments with a prime superscript (′) represents doubling of peaks due to conformational heterogenity. Horizontal dotted lines connect resonances of side chain amide protons. See text for details. c R₁, R_1ρ relaxation rates and steady-state heteronuclear {¹H} - ¹⁵N NOEs for ¹⁵N backbone nuclei of MazE6, plotted against residue number. Low R_1ρ relaxation rates and steady-state {¹H} - ¹⁵N heteronuclear NOE values for the C-terminal residues further confirm its disordered (dynamic) nature in solution. Blank spaces correspond to residues for which data is missing. Source data are provided in the Supplementary Data 1.