Table 2.

Molecular Characteristics

Patient #	Next generation sequencing	Chromosomal microarray	Methylation profiling	Histologic diagnosis	Integrated diagnosis
1	Seven variants of uncertain significance	Gains in chromosome 5	Central neurocytoma, Calibrated score: 0.999	Central atypical neurocytoma	Central atypical neurocytoma
2	EWSR-ATF1 gene fusion MUTYH mutation	No significant findings	No match	Central atypical neurocytoma with EWSR-ATF1 gene fusion and MUTYH mutation	Neuroepithelial neoplasm with EWSR1-ATF gene fusion and MUTYH mutation
3	No clinically significant findings	No significant findings	Inadequate sample given cystic nature of tumor	Central neurocytoma	Central Neurocytoma
4	No clinically significant findings	Gains in chromosomes 5, 7, 11, 12, 19, 20, X, and Y	Ganglioglioma, calibrated score: 0.927	Extraventricular neurocytoma	Altered diagnosis to ganglioglioma
5	One variant of uncertain significance in the ATM gene	Gains in chromosomes 6, 7, 8, X, Y	Ganglioglioma, calibrated score: 0.766	Extraventricular neurocytoma	Altered diagnosis to ganglioglioma