Fig. 2.

Fhl2^−/− mice have improved glucose tolerance and insulin secretion. (a) Body weight of WT and Fhl2^−/− mice during 14 weeks of standard chow diet. (b) Fasted plasma insulin of 8-week-old WT and Fhl2^−/− mice. (c) Blood glucose levels during OGTT in 16-week-old WT and Fhl2^−/− mice, with calculated AUCs. (d) Blood glucose levels during IPGTT in 20-week-old WT and Fhl2^−/− mice, with calculated AUCs. (e) Plasma insulin of mice during the IPGTT, with calculated AUCs. (f) Blood glucose levels during ITT in 22-week-old WT and Fhl2^−/− mice, with calculated AUCs. Data are presented as mean ± SEM; *p<0.05