. 2022 Jun 4;19(5):927–960. doi: 10.1007/s13770-022-00459-z

Table 5.

Skin tissue engineering applications

Nanocomposite	Synthesis method	Highlights	References
CSH/PAA/Dch-PPy	Free-radical polymerization	Mimic human skin	[20, 55]
CS-g-PA/PEG-co-PGS	The facile approach of mixing under physiological conditions	Antibacterial properties	[20, 86]
		Wound healing
		in vivo clotting
		Collagen deposition
GO-PLGA/Col hybrid fiber sheets	Dual electrospinning method	Wound healing	[50]
GO-PLGA/Col hybrid fiber sheets	Dual electrospinning method	Increased proliferation of human dermal fibroblasts (HDFs)	[50]
3D GF	CVD with Ni foam as a template	Wound healing	[60]
		Enhance growth and proliferation of MSCs
		Reduce scar formation
		Guides the wound healing process
HA-DA/rGO hydrogel dressing	EDC/NHS coupling	Wound healing	[61]
		Enhances vascularization
		Improve granulation tissue thickness
		Collagen deposition
GO-PEG/Que/Col scaffold	ECD-catalyzed amide formation under ultrasonication	Diabetic wound healing	[63]
		Promote collagen deposition
		Angiogenesis in diabetic wound repair
		Amplify attachment and proliferation of MSCs
MoSe₂-NIPAM hydrogels	Simultaneous exfoliation and functionalization	Wound repair	[57]
MoSe₂-NIPAM hydrogels	Simultaneous exfoliation and functionalization	Tunable dual stimuli-responsive behavior	[57]
CS-Gel/nZnO scaffolds	In situ synthesis of nZnO NPs	Possess antibacterial and biodegradable properties	[56]