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. 2022 Sep 2;13:928359. doi: 10.3389/fimmu.2022.928359

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Copyright © 2022 Jin, Chen, Wu, Lu, Li, Fu, Wang and Cui

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Frequencies of B cell subsets in SLE patients. (A), Analysis of B cell subsets by flow cytometry; (B), Percentage of naïve B cells (CD19⁺CD27^-IgD⁺), plasmablasts (CD19⁺CD27⁺CD20^-CD38⁺), class-switched memory B cells (CD19⁺CD27⁺IgD^-), and IgM memory B cells (CD19⁺CD27⁺IgD⁺) in SLE patients; (C), The correlations between percentage of Plasmablast and SLEDAI, ANA titer. Horizontal lines show the median. Statistically significant differences are indicated by the P value, *P<0.05;**P<0.01;***P<0.001.