Table 1.
Epidemiological characteristics and etiologic data of inpatients with HFMD in 2014 to 2020.
| 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | Total | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n = 1175(%) | n = 1048(%) | n = 1783(%) | n = 1277(%) | n = 1081(%) | n = 622(%) | n = 387(%) | N = 7373(%) | |||||||||
| Age group (yr) | ||||||||||||||||
| <1 | 43 | (3.7) | 19 | (1.8) | 8 | (0.4) | 4 | (0.3) | 2 | (0.2) | 6 | (1.0) | 5 | (1.3) | 87 | (1.2) |
| 1~ | 559 | (47.6) | 571 | (54.5) | 991 | (55.6) | 765 | (59.9) | 703 | (65.0) | 379 | (60.9) | 236 | (61.0) | 4204 | (57.0) |
| 2~ | 331 | (28.2) | 221 | (21.1) | 429 | (24.1) | 249 | (19.5) | 201 | (18.6) | 133 | (21.4) | 84 | (21.7) | 1648 | (22.4) |
| 3~ | 139 | (11.8) | 144 | (13.7) | 217 | (12.2) | 158 | (12.4) | 102 | (9.4) | 67 | (10.8) | 37 | (9.6) | 864 | (11.7) |
| 4~ | 62 | (5.3) | 55 | (5.2) | 77 | (4.3) | 66 | (5.2) | 46 | (4.3) | 22 | (3.5) | 20 | (5.2) | 348 | (4.7) |
| >5 | 41 | (3.5) | 38 | (3.6) | 61 | (3.4) | 35 | (2.7) | 27 | (2.5) | 15 | (2.4) | 5 | (1.3) | 222 | (3.0) |
| Age (mo) | ||||||||||||||||
| Median (IQR) | 21(15-32) | 21(16-34) | 21(16-32) | 22(17-32) | 20(15-28) | 20(15-29) | 20(16-30) | 21(16-31) | ||||||||
| Mean ± SD | 26.00 ± 14.37 | 26.65 ± 14.85 | 26.38 ± 14.16 | 25.55 ± 14.16 | 24.41 ± 13.98 | 24.51 ± 14.23 | 24.40 ± 12.21 | 25.66 ± 14.20 | ||||||||
| Gender | ||||||||||||||||
| Male | 772 | (65.7) | 633 | (60.4) | 1145 | (64.2) | 815 | (63.8) | 695 | (64.3) | 374 | (60.1) | 235 | (60.7) | 4669 | (63.3) |
| Female | 403 | (34.3) | 415 | (39.6) | 638 | (35.8) | 462 | (36.2) | 386 | (35.7) | 248 | (39.9) | 152 | (39.3) | 2704 | (36.7) |
| M/F ratio | 1.92:1 | 1.53:1 | 1.79:1 | 1.76:1 | 1.80:1 | 1.51:1 | 1.55:1 | 1.73:1 | ||||||||
| Hosting classification | ||||||||||||||||
| Scatter children | 849 | (72.3) | 716 | (68.3) | 1305 | (73.2) | 951 | (74.5) | 830 | (76.8) | 452 | (72.7) | 293 | (75.7) | 5396 | (73.2) |
| Childcare | 311 | (26.5) | 309 | (29.5) | 441 | (24.7) | 306 | (24.0) | 235 | (21.7) | 156 | (25.1) | 89 | (23.0) | 1847 | (25.1) |
| In school | 12 | (1.0) | 22 | (2.1) | 34 | (1.9) | 16 | (1.3) | 15 | (1.4) | 13 | (2.1) | 3 | (0.8) | 115 | (1.6) |
| Others | 3 | (0.3) | 1 | (0.1) | 3 | (0.2) | 4 | (0.3) | 1 | (0.1) | 1 | (0.2) | 2 | (0.5) | 15 | (0.2) |
| Etiology | ||||||||||||||||
| Negative | 238 | (20.3) | 225 | (21.5) | 388 | (21.8) | 211 | (16.5) | 186 | (17.2) | 122 | (19.6) | 67 | (17.3) | 1437 | (19.5) |
| EV71 | 363 | (30.9) | 302 | (28.8) | 493 | (27.7) | 210 | (16.4) | 113 | (10.5) | 79 | (12.7) | 39 | (10.1) | 1599 | (21.7) |
| CV-A16 | 194 | (16.5) | 164 | (15.6) | 319 | (17.9) | 190 | (14.9) | 81 | (7.5) | 44 | (7.1) | 36 | (9.3) | 1028 | (13.9) |
| Others | 380 | (32.3) | 357 | (34.1) | 583 | (32.7) | 666 | (52.2) | 701 | (64.8) | 377 | (60.6) | 245 | (63.3) | 3309 | (44.9) |
| Severity | ||||||||||||||||
| Mild | 998 | (84.9) | 939 | (89.6) | 1615 | (90.6) | 1197 | (93.7) | 1030 | (95.3) | 590 | (94.9) | 370 | (95.6) | 6739 | (91.4) |
| Severe | 177 | (15.1) | 109 | (10.4) | 168 | (9.4) | 80 | (6.3) | 51 | (4.7) | 32 | (5.1) | 17 | (4.4) | 634 | (8.6) |
CV-A16 = coxsackievirus A16, EV71 = enterovirus 71, HFMD = hand-foot-and-mouth disease, IQR = inter-quartile range, SD = standard deviation.