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. 2022 Sep 2;9:976537. doi: 10.3389/fcvm.2022.976537

TABLE 3.

Hazard ratios (95%CI) of incident stroke by sleep duration and daytime napping.

Variable N case/total Incidence
rates,% (95%CI)
Incident stroke, adjusted HR (95%CI)
Univariate model Age and gender adjusted Multivariable adjusted Multivariable adjusted
Nighttime sleep duration, hours/night
≤6 h 77/3,206 2.40 (1.90,2.99) 1.51 (1.05, 2.16) * 1.41 (0.98, 2.02) 1.65 (1.04, 2.61) * 1.65 (1.04, 2.61) *
6 to ≤8 h 49/3,065 1.60 (1.19, 2.11) 1.000 1.000 1.000 1.000
>8 h 10/606 1.65 (0.79,3.01) 1.04 (0.52, 2.04) 1.02 (0.52, 2.01) 1.39 (0.65, 2.94) 1.38 (0.65, 2.93)
Daytime napping, minutes
0 66/3,148 2.10 (1.63, 2.66) 1.11 (0.77, 1.61) 1.18 (0.81, 1.73) 1.36 (0.85, 2.16) 1.36 (0.86, 2.18)
1 to ≤60 min 48/2,543 1.89 (1.39, 2.49) 1.000 1.000 1.000 1.000
>60 min 22/1,186 1.85 (1.17, 2.80) 0.98 (0.59, 1.63) 0.90 (0.54, 1.51) 0.94 (0.49, 1.82) 0.94 (0.49, 1.82)
Total sleep duration, hours/day
<7 h 62/2,443 2.54 (1.95, 3.24) 1.53 (1.07, 2.18) * 1.52 (1.06, 2.18) * 1.61 (1.03, 2.52) * 1.62 (1.03, 2.53) *
7 to ≤9 h 60/3,598 1.67 (1.27, 2.14) 1.000 1.000 1.000 1.000
>9 h 14/836 1.67 (0.92, 2.79) 1.01 (0.56, 1.80) 0.98 (0.54, 1.75) 1.11 (0.56, 2.18) 1.11 (0.56, 2.17)

HR, hazard ratio; CI, confidence interval. *P < 0.05.

Adjusted for age, gender, educational level, marital status, area of residence, and behaviors including smoking, drinking, and physical activity.

Adjusted for age, gender, educational level, marital status, area of residence, behaviors including smoking, drinking, and physical activity, along with additional adjustment for self-reported diagnosis of stroke, dyslipidemia, hypertension, diabetes or high blood sugar, BMI, waist circumference, triglycerides, HDL-C, systolic and diastolic blood pressure, fasting plasma glucose and HbA1c levels.

Bold values indicate the positive results of the study.