Loss of Idh3b did not affect visual function and retinal health in mice.A and B, representative scotopic (0.8 cd∗s/m2) and photopic (10 cd∗s/m2) ERGs of Idh3b KO and Idh3b HET (control) at P250. N ≥ 4. C and D, scotopic ERG and photopic ERG analysis under different light intensities for HET and KO mice at P250. N ≥ 4. E, representative retinal H&E images from HET and KO mice at P250. F, number of nuclei in outer nuclei layer (ONL) at different positions of the eye. N ≥ 3. G and H, thickness of inner segment (IS) and outer segment (OS) at different positions of the eye. N ≥ 3. Data are all represented as mean ± SD; t test. ERG, electroretinogram; HET, heterozygous.