Figure 5.
IDH3B is essential for spermiogenesis.A and B, representative H&E images for testicular sections from mice at P50. A′ and B′, late-stage testicular tubule with mature spermatozoa. Spermatid (R): round spermatid, spermatid (E): elongated spermatid. C, quantification of different sperm cell populations from the HET and KO testes. N of tubules = 20, ∗p < 0.05. Data are represented as mean ± SD; t test. D–M, periodic acid–Schiff stain (PAS) for staging sperm differentiation in testes. Arrowheads pointed to the acrosome. HET, heterozygous; IDH3B, isocitrate dehydrogenase 3B.