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. 2022 Aug 17;298(9):102387. doi: 10.1016/j.jbc.2022.102387

Figure 8.

Figure 8

Loss of Idh3b dramatically disrupted cellular metabolism in testis but not the heart.A, fold change of TCA cycle metabolites in testis from KO mice at P50. N ≥ 6, ∗p < 0.05. B, fold change of TCA cycle metabolites in the heart from KO mice at P50. N ≥ 8, ∗p < 0.05. C, multivariant analysis of metabolomic study for testis by LC/MS. N = 6. D, volcano plot of metabolites from the testes by LC/MS. N ≥ 6, fold change ≥1.5, p < 0.05. E, heatmap for top 15 changed metabolites. N = 6, fold change ≥1.5, p < 0.05. F, multivariant analysis of metabolites from the heart. N ≥ 8. G, volcano plot of metabolites from the heart by LC/MS. N ≥ 8, fold change ≥1.5, p < 0.05. Data are all represented as mean ± SD; t test. TCA, TCA, tricarboxylic acid.