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. 2022 Sep 2;10:971739. doi: 10.3389/fbioe.2022.971739

TABLE 2.

The metabolomic changes in Caco-2 cells during coculture with C. difficile. Metabolomic analysis was performed in quadruplicate.

Name Log2FC (C. difficile/control)
Glutamate −1.4062
Cysteine −1.1766*
ATP −5.3137***
Glutathione −6.9352***
Glucose −1.3254*
d-glucose-6-phosphate −3.7082***
d-fructose-6-phosphate −3.8165***
Citrate −2.743***
Malate −2.2069***
NADH −2.0183*
Acetyl-CoA −1.9625
Oxaloacetate 2.0266
Pyruvate 0.82646

*p < 0.05, **p < 0.01, ***p < 0.001.