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. 2022 Aug 19;24(4):351. doi: 10.3892/ol.2022.13471

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Expression of the E2F family in ccRCC. (A) Heatmap displaying the expression of E2Fs in ccRCC using the total tumor (n=530) and normal (n=72) ccRCC data from TCGA. (B) Scatter plot displaying the expression of tumor tissues (n=530) and normal tissues (n=72) from TCGA. (C) Scatter plot displaying the expression of tumor tissues (n=72) and normal tissues (n=72) from dataset GSE36895. (D) Scatter plot displaying the expression of tumor tissues (n=29) and normal tissues (n=23) from dataset GSE53757. (E) Reverse transcription-quantitative PCR showing the expression of E2Fs in 10 paired ccRCC and normal samples. Data are presented as the mean ± SEM. *P<0.05, **P<0.01, ***P<0.001 and ****P<0.0001. ccRCC, clear cell renal cell carcinoma; TCGA, The Cancer Genome Atlas.