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. 2022 Aug 19;24(4):351. doi: 10.3892/ol.2022.13471

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Mechanism of E2Fs dysregulation in patients with ccRCC. (A) Mutation rate of the E2F family in patients with ccRCC. (B) Heatmap displaying E2F expression levels and DNA methylation levels in ccRCC tissues and normal tissues. (C) Association between E2F expression levels and DNA methylation levels in ccRCC tissues. (D) Association between E2F expression level and copy number in ccRCC tissues. ccRCC, clear cell renal cell carcinoma.