TABLE 1.

Major classes of medicines, drug mix, annual volume, and expenditure in 2012 and in 2018 and variations in the period. Minas Gerais, Brazil.

Major classes of medicines a	Drug mix								Annual volume (millions)			Annual expenditure USD (millions) b
	Chemical substance			Pharmaceutical products c
	2012	2018	Variation d (%)	2012		2018		Total variation d (%)	2012	2018	Variation d (%)	2012	2018	Variation d (%)
				Total	%IS e	Total	%IS e
A-alimentary tract and metabolism	8	10	25	9	0	26	15	189	237.67	153.67	−35.34	2.64	3.26	23.54
B-blood and blood forming organs	5	9	80	6	0	14	50	133	82.72	78.12	−5.56	0.58	1.15	96.98
C—cardiovascular system	18	24	33	24	0	47	13	96	816.59	543.50	−33.44	8.85	8.90	0.56
D—dermatologicals	2	8	300	2	0	11	0	450	1.72	0.84	−50.99	0.30	0.34	13.37
G—genito-urinary system and sex hormones	6	6	0	6	33	7	0	17	37.44	0.67	−98.21	1.52	0.24	-84.47
H—systemic hormonal preparations, excl. Sex hormones and insulins	3	6	100	6	0	14	28	133	37.05	51.89	40.08	1.29	1.75	35.49
J—anti-infectives for systemic use	12	13	8	18	11	27	22	50	57.59	40.02	−30.52	4.14	5.21	25.85
M—musculo-skeletal system	3	3	0	6	0	6	0	0	37.84	25.18	−33.45	0.96	0.88	−8.51
N—nervous system	19	24	26	32	6	52	27	63	346.11	256.81	−25.80	7.61	10.51	38.13
P—anti-parasitic products, insecticides, and repellents	6	4	−33	10	0	7	0	-30	9.57	5.38	−43.81	0.37	0.36	−2.75
R—respiratory system	5	8	60	9	0	17	12	89	17.97	15.40	−14.27	1.99	2.15	7.68
S - sensory organs	3	6	100	3	0	7	0	133	0.15	0.09	−41.97	0.13	0.06	−54.88
V—various	1	6	500	1	0	8	75	700	0.10	0.23	123.25	0.05	0.05	4.45
Total	91	127	40	132	5	243	20	84	1,682.51	1,171.80	-30.35	30.43	34.84	14.50

^aATC, first level.

^b1USD, 3.8742 BRL.

^cPharmaceutical products including all chemical substances in their different dosage forms and strengths.

^dVariation = [(∑2018-∑2012)/∑2012]∗100.

^eIS: Injectable Solution.