. 2022 Sep 15;5(9):e2231790. doi: 10.1001/jamanetworkopen.2022.31790

Table 2. Symptom Dynamics of COVID-19 Survivors According to Disease Severity.

Categories	No. of symptoms		Patients, No. (%)			P value, severe vs nonsevere disease
Categories	1-y follow-up	2-y follow-up	Enrolled patients	Severe disease	Nonsevere disease	P value, severe vs nonsevere disease
Total	NA	NA	1864 (100.0)	505 (100.0)	1359 (100.0)	NA
Symptoms persist^a	≥1	≥1	224 (12.0)	89 (17.6)	135 (9.9)	<.001
Symptom relief^b	≥1	0	582 (31.2)	175 (34.7)	407 (29.9)	.05
New-onset symptoms^c	0	≥1	146 (7.8)	34 (6.7)	112 (8.2)	.28
No symptoms^d	0	0	912 (48.9)	207 (41.0)	705 (51.9)	<.001

Abbreviation: NA, not applicable.

^{^a}

Refers to patients with at least 1 symptom at both 1-year and 2-year follow-up.

^{^b}

Refers to patients with at least 1 symptom at 1-year follow-up but without any symptoms at 2-year follow-up.

^{^c}

Refers to patients without any symptoms at 1-year follow-up, but reported at least 1 symptom at 2-year follow-up, including patients who had a symptom that was reported as a mild problem at year 1, but at 2-year follow-up was reported as moderate or severe problem.

^{^d}

Refers to patients with no symptoms at any follow-up.