Table 2.
Differential metabolites of intestinal contents in each group at 7 days (|Log[2]FC| ≥ 1).
| Metabolites | VIP | p-value | Log2FC | HMDB | KEGG | |
|---|---|---|---|---|---|---|
| IS-C | Maltose | 1.46 | 1.46E-02 | −1.98 | HMDB0000163 | C00208 |
| 3-Cyanoalanine | 1.74 | 3.66E-04 | −1.95 | METPA0300 | C02512 | |
| Glutaric acid | 1.32 | 2.91E-02 | −1.94 | HMDB0000661 | C00489 | |
| 3-Hydroxybenzoic acid | 1.35 | 2.71E-02 | −1.72 | HMDB0002466 | C00587 | |
| Glutamine[-H2O] | 1.78 | 1.34E-04 | −1.60 | - | - | |
| 4-Hydroxybenzoic acid | 1.49 | 9.01E-03 | −1.58 | HMDB0000500 | C00156 | |
| 4-Hydroxybutyric acid | 1.33 | 3.27E-02 | −1.13 | HMDB0000710 | C00989 | |
| 2-Deoxyinosine | 1.36 | 1.93E-02 | 1.29 | HMDB0000071 | C05512 | |
| Galactose | 1.50 | 1.11E-02 | 1.32 | HMDB0000143 | C00984 | |
| 2-Deoxyguanosine | 1.32 | 3.02E-02 | 1.35 | HMDB0000085 | C00330 | |
| Glycerol-3-phosphate | 1.22 | 3.43E-02 | 1.44 | HMDB0000126 | C00093 | |
| Cystine | 1.42 | 1.49E-02 | 1.48 | HMDB0000192 | C00491 | |
| Orotic acid | 1.49 | 1.50E-02 | 3.11 | HMDB0000226 | C00295 | |
| Lactose | 1.53 | 1.27E-02 | 3.22 | HMDB0000186 | C00243 | |
| EE-IS | Succinic acid | 1.48 | 2.72E-02 | −1.29 | HMDB0000254 | C00042 |
| Citric acid | 1.60 | 2.00E-02 | 1.02 | HMDB0000094 | C00158 | |
| Hexanoic acid | 1.86 | 3.67E-03 | 1.37 | HMDB0000535 | C01585 | |
| 4-Methylvaleric acid | 1.64 | 2.83E-02 | 1.63 | HMDB0000689 | - | |
| 3-Hydroxyphenylacetic acid | 1.94 | 9.78E-04 | 1.93 | HMDB0000440 | C05593 | |
| Glutaric acid | 1.98 | 1.39E-03 | 2.04 | HMDB0000661 | C00489 | |
| APS-IS | 3,4-Dihydroxyphenylacetic acid | 1.62 | 1.20E-02 | −2.49 | HMDB0001336 | C01161 |
| Malic acid | 1.42 | 4.97E-02 | 1.00 | HMDB0000156 | C00149 | |
| 4-Hydroxyphenylethanol | 1.78 | 2.67E-03 | 1.01 | HMDB0004284 | C06044 | |
| 2-Hydroxyglutaric acid | 1.40 | 4.71E-02 | 1.22 | HMDB0000694 | C03196 | |
| 4-Methylthio-2-ketobutyric acid | 1.88 | 3.77E-04 | 1.50 | HMDB0001553 | C01180 | |
| 2-Ketoglutaric acid | 1.68 | 6.60E-03 | 1.73 | HMDB0000208 | C00026 | |
| 2-Ketoisovaleric acid | 1.74 | 3.75E-03 | 1.84 | HMDB0000019 | C00141 | |
| 3-Methyl-2-ketovaleric acid | 1.81 | 1.54E-03 | 1.88 | HMDB0000491 | C03465 | |
| 2-Ketoisocaproic acid | 1.87 | 5.55E-04 | 1.88 | HMDB0000695 | C00233 |
The underlined value means that the number has corresponding information in the database.