Table 3.

Differential metabolites of intestinal contents in each group at 14 days (|Log[2]FC| ≥1).

	Metabolites	VIP	p-value	Log2FC	HMDB	KEGG
IS-C	2-Ketoglutaric acid	1.39	4.11E-02	−1.61	HMDB0000208	C00026
	Beta-glutamic acid	1.50	1.77E-02	−1.35	-	-
	4-Hydroxyphenylacetic acid	1.56	3.52E-02	1.00	HMDB0000020	C00642
	Fructofuranose	1.65	9.37E-03	1.12	-	-
	Gluconic acid	1.59	2.38E-02	1.49	HMDB0000625	C00257
	Glycyl-leucine	1.30	4.13E-02	1.63	HMDB0000759	C02155
EE-IS	2-Hydroxyglutaric acid	1.64	9.38E-03	−1.43	HMDB0000694	C03196
	2-Ketoglutaric acid	1.59	1.55E-02	−1.27	HMDB0000208	C00026
	4-Hydroxyphenylacetic acid	1.54	2.50E-02	−1.01	HMDB0000020	C00642
	3-Cyanoalanine	1.46	3.93E-02	−1.00	METPA0300	C02512
	Ethanolamine	1.52	2.50E-02	1.28	HMDB0000149	C00189
	5-Hydroxyindoleacetic acid	1.64	9.80E-03	1.43	HMDB0000763	C05635
	Coprostanol	1.47	3.46E-02	2.25	HMDB0000577	-
APS-IS	3-Hydroxybenzoic acid	1.48	1.43E-02	−2.77	HMDB0002466	C00587
	Fructose	1.74	1.86E-03	−1.59	HMDB0000660	C02336
	2,3-Dihydroxybutane	1.47	2.80E-02	−1.52	HMDB0003156	C00265
	Xylitol	1.47	1.34E-02	−1.25	HMDB0002917	C00379
	Glucose	1.57	1.50E-02	−1.22	HMDB0000122	C00031
	Fructofuranose	1.51	4.08E-02	−1.17	-	-
	Adenine	1.44	4.52E-02	1.13	HMDB0000034	C00147
	2-Deoxyadenosine	1.34	4.00E-02	1.15	HMDB0000101	C00559
	Stigmastanol	1.59	1.46E-02	1.40	HMDB0000494	-
	Octanoic acid	1.51	1.85E-02	1.68	HMDB0000482	C06423
	p-cresol	1.43	3.28E-02	1.68	HMDB0001858	C01468
	2-Ketoglutaric acid	1.55	1.91E-02	1.81	HMDB0000208	C00026
	Uric acid	1.44	2.05E-02	1.85	HMDB0000289	C00366

The underlined value means that the number has corresponding information in the database.