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. 2022 Sep 2;13:894325. doi: 10.3389/fgene.2022.894325

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Copyright © 2022 Chen, Yao, Sun, Wang, Yue, Cui, Yu, Xu and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kaplan–Meier survival analysis of the prognostic model. Invalids in both datasets were divided into high-risk (red) and low-risk (blue) groups, applying the median risk score as the threshold. (A,B) In the TCGA cohort, the survival probability of the low-risk group was higher than that of the high-risk group (p < 0.001). The AUCs at 1-, 3-, and 5-years were 0.788, 0.628, and 0.634, respectively. (C,D) This prognostic model was verified in the GEO cohort. The survival probability of low-risk group was higher than that of high-risk group (p = 0.0002). The AUCs at 1 year, 2 years, and 3 years were 0.735, 0.699, and 0.73, respectively.