TABLE 2.

Indications for treatment of Hashimoto thyroiditis in pregnancy (adapted from Lee and Pearce⁹⁵ and Alexander et al²⁶)

Laboratory data	Treatment
TPOAbs negative, TSH ≥10 mIU/ml	Treat with levothyroxine
TPOAbs negative and TSH between 4 mIU (or pregnancy specific upper reference) and 10 mIU/ml	Consider treatment with levothyroxine
TPOAbs positive, TSH exceeding the pregnancy-specific range or >4 mIU/ml	Treat with levothyroxine
TPOAbs positive and TSH between 2.5 and 4 mIU/ml (or pregnancy-specific upper reference range)	Consider treatment with levothyroxine
Isolated hypothyroxinemia	Do not treat with levothyroxine

Abbreviations: see TABLE 1 and FIGURE 1