Table 2.
Reported glycoside hydrolases for biofilm dispersion
| Glycoside hydrolase | Targeting glycosidic linkage | Monosaccharide composition of the polysaccharides |
|---|---|---|
| Dispersin B | GlcNAc -(β-1,6)- GlcNAc |
N-acetyl-D-glucosamine |
| α-Amylase | Glc-(α-1,4)-Glc | D-glucose |
| Cellulase | Glc-(β-1,4)-Glc | D-glucose |
| PslG | Manp-(β-1,3)- Manpa | D-mannose, D-glucose and L-rhamnose |
| PelA | (1,4)b | Partially de-N-acetylated N-acetylgalactosamine |
| β-Mannosidase | Man-(β-1,4)-Man | D-mannose |
| α-Mannosidase | Man-(α-1,3)-Man | D-mannose |
| PgaB | GlcN-(β-1,6)-GlcN | D-glucosamine |
| Ega3 | GalN-(α-1,4)-GalN | D-galactosamine |
| Sph3 | GalNAc-(α-1,4)-GalNAc | N-acetyl-D-galactosamine |
| CcsZ | Glc-(β-1,4)-Glc | D-glucose |
| PssZ | ManN-(β-1,4)-ManN | D-mannosamine |
a
The targeting glycosidic linkage of PslG is predicted.
b
PelA enzyme works on Pel, a linear cationic polysaccharide composed of partially de-N-acetylated 1,4 linked N-acetylgalactosamine.