Table 5.
Wild bootstrapping multivariate regression of hypertension with humoral and cellular response parameters as dependent variables in infected health care workers.
| Cellular and humoral response parameters | B | Bias | Std. Error | Sig. | BCa 95% Confidence Interval | |
| Lower | Upper | |||||
| SARS-CoV-2 IgG-Ab (S1) (BAU/ml) a | 238.119 | -5.462 | 80.72 | 0.013 | 91.835 | 376.501 |
| SARS surrogate neutralization test (%) b | 16.544 | -.891 | 6.747 | 0.020 | 4.892 | 26.704 |
| Spike-N-Term LTT (SI) c | 6.599 | 0.062 | 3.153 | 0.078 | 0.325 | 12.943 |
| Spike-C-Term LTT (SI) d | 4.792 | 0.058 | 2.456 | 0.066 | 0.045 | 9.805 |
The multiple regression models were performed with humoral and cellular response parameters as one dependent variable, respectively, i.e., SARS-CoV-2 IgG-Ab (S1) (BAU/ml) in model a, and R2 of the model is 0.255; SARS surrogate neutralization test (%) in model b, and R2 of the model is 0.194; Spike-N-Term LTT (SI) in model c, and R2 of the model is 0.304; Spike-C-Term LTT (SI) in model d, and R2 of the model is 0.260. We include confounding factors such as age (years), sex (M/F), BMI (body mass index, calculated as weight in kilograms divided by height in meters squared), diabetes (yes/no), hypertension (yes/no), chronic obstructive pulmonary disease (COPD) (yes/no), asthma (yes/no), smoking (yes/no), time from infection to blood collection (days) into the models. BCa, Bias-corrected and accelerated. Details of the individual models are shown in Supplementary Table 1 .