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. 2022 Sep 2;13:919544. doi: 10.3389/fphys.2022.919544

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Copyright © 2022 Sierra, Martínez Galán, de Sousa, de Menezes, Branquinho, Neves, Arata, Bittencourt, Barbeiro, de Souza, Pesquero and Cury-Boaventura.

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Inflammatory mediators in II, ID and DD genotypes. Plasma concentrations of MCP-1 (A), IL-10 (B), IL-8 (C), MIP-1alpha (D), TNF-alpha (E) and VEGF (F) before, immediately after, 24 and 72 h after the race were determined. Values are presented as mean and standard error of the mean of seven runners with genotype II, 22 runners with ID runners, and 14 runners with genotype DD. Comparisons between genotypes and time were performed by two-way repeated measures ANOVA and Sidak’s multiple comparisons test.