TABLE 2.
Univariable and multivariable Cox analysis for evaluating the association between considered covariates at inclusion and complete or partial remission of the nephrotic syndrome.
| Characteristics | Univariable | Multivariable | ||
|---|---|---|---|---|
| Hazard ratio (95% CI) | p-value | Hazard ratio (95% CI) | p-value | |
| Demography and clinical parameters | ||||
| Age (years) | 1.003 (0.991–1.016 | 0.6050 | — | — |
| Sex (M/F) | 2.120 (1.439–3.124) | 0.0001 | 1.823 (1.100–-3.021) | 0.0198 |
| BMI (kg/m2) | 1.016 (0.973–1.061) | 0.4654 | — | — |
| Systolic BP (mmHg) | 0.993 (0.982–1.004) | 0.2321 | — | — |
| Diastolic BP (mmHg) | 0.980 (0.961–0.999) | 0.0396 | 1.001 (0.977-–1.027) | 0.9140 |
| Reported duration of proteinuria (mo) | 0.998 (0.996–1.001) | 0.3002 | — | — |
| Laboratory parameters | ||||
| Serum creatinine (mg/dL) | 0.604 (0.432–0.844) | 0.0031 | 0.570 (0.370–0.878) | 0.0108 |
| Serum albumin (g/dL) | 1.092 (0.842–1.417) | 0.5066 | — | — |
| Serum proteins (g/dL) | 1.059 (0.855–1.312) | 0.6010 | — | — |
| Total cholesterol (mg/dL) | 0.998 (0.995 – 1.000) | 0.0680 | — | — |
| HDL cholesterol (mg/dL) | 1.006 (0.996–1.017) | 0.2469 | — | — |
| Triglycerides (mg/dL) | 0.995 (0.993–0.998) | 0.0002 | 0.996 (0.994–0.999) | 0.159 |
| Proteinuria (g/24 h) | 0.952 (0.920–0.985) | 0.0043 | 0.951 (0.904–1.001) | 0.054 |
| Iohexol measured GFR (ml/min/1.73 m2) | 1.001 (0.994–1.009) | 0.7346 | — | — |
| Anti-PLA2R1 parameters | ||||
| Anti-PLA2R1 titer (RU/ml) | 0.999 (0.998–1.00) | 0.0912 | 0.999 (0.999–1.00) | 0.0766 |