Table 1.
Variable | All cases (73) | Median OS ± SD (months) | UV | UV | MV | MV |
---|---|---|---|---|---|---|
P value | HR (95% CI) | P value | HR (95% CI) | |||
Sex | ||||||
Male | 17 | 20.88 ± 17.613 | 0.011 | 2.700(1.261-5.778) | 0.295 | |
Female | 56 | 27.52 ± 15.657 | ||||
Age | ||||||
>60 | 25 | 24.12 ± 14.692 | 0.317 | 1.466(0.693-3.099) | ||
<=60 | 48 | 26.9375 ± 17.079 | ||||
Smoking | ||||||
No | 46 | 25.3 ± 17.433 | 0.094 | 2.082(0.882-4.911) | 0.72 | |
Yes | 27 | 27.11 ± 14.262 | ||||
Drinking | ||||||
No | 55 | 24.80 ± 17.297 | 0.234 | 1.800(0.683-4.739) | ||
Yes | 18 | 29.56 ± 12.263 | ||||
Tumor size | ||||||
<6 | 44 | 29.227 ± 16.127 | 0.074 | 1.968(0.936-4.138) | 0.209 | |
>=6 | 29 | 21.03 ± 15.426 | ||||
LNs metastasis | ||||||
No | 65 | 27.83 ± 15.969 | 3.77E-06 | 7.896(3.288-18.959) | 7.00E-06 | 7.901(3.214-19.419) |
Yes | 8 | 10.88 ± 9.643 | ||||
Satellite stove | ||||||
Negative | 54 | 27.98 ± 15.559 | 0.053 | 2.151(0.991-4.667) | 0.048 | 2.244(1.008-4.996) |
Positive | 19 | 20.26 ± 17.243 | ||||
Vascular invasion | ||||||
Negative | 56 | 29.45 ± 15.984 | 0.018 | 2.689(1.185-6.104) | 0.425 | |
Positive | 17 | 14.53± 11.364 | ||||
Nerve invasion | ||||||
Negative | 61 | 27.8716.359 | 0.005 | 3.378(1.436-7.948) | 0.271 | |
Positive | 12 | 16.33 ± 12.168 | ||||
T stage | ||||||
T1+2 | 50 | 29.16 ± 16.07 | 0.026 | 2.361(1.109-5.028) | ||
T3+4 | 23 | 19.04 ± 14.698 | ||||
TNM stage | ||||||
I+II | 48 | 30.06 ± 15.759 | 0.004 | 2.987(1.409-6.334) | 0.748 | |
III+IV | 25 | 18.12 ± 14.438 | ||||
HBs antigen | ||||||
Negative | 27 | 26.04 ± 18.797 | 0.274 | 1.515(0.720-3.185) | ||
Positive | 46 | 25.93 ± 14.782 | ||||
Margins | ||||||
Negative | 67 | 26.90 ± 16.449 | 0.298 | 1.911(0.564-6.457) | ||
Positive | 6 | 15.67 ± 9.668 | ||||
NDUFC1 | ||||||
Low | 25 | 32.60 ± 17.376 | 0.016 | 3.330(1.252-8.858) | 0.043 | 2.747(1.032-7.307) |
High | 48 | 22.52 ± 14.662 |
IHC, immunocytochemistry; LNs, lymph nodes; T, tumor; TNM, tumor-node-metastasis; HBs, hepatitis B surface; N, number; OS, overall survival; SD, standard deviation; UV, Univariable; HR, hazard ratio; CI, confidence interval; MV, multivariable.