Table 1.
Baseline characteristics of patients with cervical cancer.
| Variables | Training set | Validation set | χ2 | P |
|---|---|---|---|---|
| n = 10,050 (%) | n = 4,306 (%) | |||
| Age | 2.14 | 0.54 | ||
| ≤39 | 2503 (24.90) | 1137 (26.40) | ||
| 40-59 | 4823 (47.99) | 2005 (46.56) | ||
| 60-79 | 2345 (23.33) | 988 (22.94) | ||
| ≥80 | 379 (3.77) | 176 (4.08) | ||
| Race | 0.91 | 0.64 | ||
| White | 7495 (74.57) | 3137 (72.85) | ||
| Black | 1450 (14.43) | 650 (15.09) | ||
| Others | 1028 (10.23) | 480 (11.14) | ||
| Grade | 0.65 | 0.89 | ||
| I | 853 (8.48) | 374 (8.68) | ||
| II | 3202 (31.86) | 1340 (31.19) | ||
| III | 3103 (30.97) | 1298 (30.14) | ||
| IV | 123 (1.22) | 83 (1.92) | ||
| Histology | 0.23 | 0.97 | ||
| SCC | 7721 (76.82) | 3243 (75.31) | ||
| AC | 1261 (12.54) | 546 (12.68) | ||
| ASC | 267 (2.65) | 146 (3.39) | ||
| NOS | 801 (7.97) | 371 (8.61) | ||
| AJCC | 1.43 | 0.70 | ||
| I | 4478 (44.56) | 1889 (43.87) | ||
| II | 1423 (14.16) | 644 (14.95) | ||
| III | 2461 (24.49) | 1021 (23.71) | ||
| IV | 1553 (15.45) | 692 (16.07) | ||
| T stage | 2.46 | 0.48 | ||
| T0-1 | 5314 (52.87) | 2233 (51.86) | ||
| T2 | 2435 (24.22) | 1000 (23.22) | ||
| T3 | 1723 (17.14) | 765 (17.76) | ||
| T4 | 317 (3.15) | 187 (4.34) | ||
| M stage | ||||
| 0.07 | 0.94 | |||
| M0 | 8822 (87.78) | 3721 (86.41) | ||
| M1 | 1228 (12.22) | 585 (13.58) | ||
| Tumor size (cm) | 1.02 | 0.60 | ||
| <5 | 4069 (40.48) | 1687 (39.18) | ||
| 5–10 | 2610 (25.97) | 1176 (27.31) | ||
| >10 | 180 (1.79) | 81 (1.88) | ||
| Surgery | 8.51 | 0.80 | ||
| None | 4733 (47.09) | 2062 (47.88) | ||
| Local tumor destruction/excision | 1212 (12.06) | 488 (11.33) | ||
| Total hysterectomy (simple, pan-) | 2263 (22.52) | 932 (21.64) | ||
| Radical/extended hysterectomy | 1748 (17.39) | 771 (17.90) | ||
| NOS | 94 (0.93) | 53 (1.23) | ||
| The number of removed regional lymph nodes | 0.87 | 0.65 | ||
| None | 6590 (65.57) | 2847 (66.12) | ||
| 1–3 | 221 (2.19) | 82 (1.90) | ||
| ≥4 | 3116 (31.00) | 1302 (30.23) | ||
| Chemotherapy | 0.65 | 0.42 | ||
| No/Unknown | 4718 (46.94) | 2059 (47.81) | ||
| Yes | 5332 (53.05) | 2247 (52.19) | ||
| Radiotherapy | 0.02 | 0.96 | ||
| No/Unknown | 4141 (41.20) | 1811 (42.06) | ||
| Yes | 5909(58.79) | 2495(57.94) | ||
| Bone metastasis | 4.44 | 0.35 | ||
| No | 9915 (98.66) | 4185 (97.19) | ||
| Yes | 135 (1.34) | 121 (2.81) | ||
| Brain metastasis | 0.99 | 0.75 | ||
| No | 10,012 (99.62) | 4289 (99.61) | ||
| Yes | 38 (0.38) | 17 (0.39) | ||
| Liver metastasis | 1.91 | 0.17 | ||
| No | 9856 (98.07) | 4212 (41.91) | ||
| Yes | 194 (1.93) | 94 (2.18) | ||
| Lung metastasis | 3.13 | 0.77 | ||
| No | 9739 (96.90) | 4111 (95.47) | ||
| Yes | 311 (3.10) | 195 (4.53) | ||
| Marital status | 1.64 | 0.65 | ||
| Single | 3156 (31.40) | 1332 (30.93) | ||
| Married | 4051 (40.31) | 1642 (38.13) | ||
| Divorce/Separation | 1417 (14.09) | 642 (14.91) | ||
| Widowed | 895 (8.90) | 400 (9.29) | ||
Number of variables with unknown status are not shown in the table above. Details are as follows: Race (77, training set; 39, validation set); Grade (2769, training set; 1211, validation set); AJCC (135, training set; 60, validation set); T stage (261, training set; 121, validation set); Tumor size (cm) (3191, training set;1362, validation set); Regional lymph node surgery (123, training set; 75, validation set); Marital status (531, training set; 290, validation set). NOS, Not Specified.