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. 2022 Sep 16;19:228. doi: 10.1186/s12974-022-02592-x

Fig. 3.

Fig. 3

IL-6 was significantly increased in CSF of SAH patients compared to control (p < 0.01) (A). No significant change was observed between groups for peripheral serum samples (p = 0.55) (B). A selective small molecule inhibitor to target the downstream cascade of IL-6 via p-STAT3 inhibition was synthesized (C)