Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 16;41:275. doi: 10.1186/s13046-022-02475-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 2 — ETV1 promotes HCC metastasis in vitro and in vivo. (A) The efficiency of ETV1-overexpression and ETV1-knockdown in the indicated HCC cells was detected by western blotting. (B) Effects of ETV1 overexpression and knockdown on HCC cell migration and invasion. Scale bar, 100 μm. (C-H) In vivo metastatic assay. (C) The representative BLI images in the liver were shown nine weeks after implanting with indicated cells. (D) The bioluminescent signals were used to show the growth rate of liver tumors. (E) The number of metastatic lesions in the lung tissues. (F) The occurrence of lung metastasis. (G) The OS of different groups in the in vivo models. (H) Representative images of H&E staining of lung samples (indicated by arrowheads) from each group. Scale bars, 1mm(upper), 100μm (lower). * Represented p < 0.05. All data were displayed as Mean ± SD