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. 2022 Sep 16;41:275. doi: 10.1186/s13046-022-02475-2

Table 1.

Correlation between ETV1 expression and clinicopathological characteristics of HCCs in two independent cohorts of human HCC tissues

Clinicopathological variables Tumor ETV1 expression P Value Tumor ETV1 expression P Value
Negative (n = 151) Positive (n = 109) Negative (n = 154) Positive (n = 126)
Age 52.11 51.77 0.411 50.57 51.51 0.351
(11.915) (10.417) (10.053) (9.743)
Sex female 31 18 0.428 19 25 0.100
male 120 91 135 101
Serum AFP  ≤ 20 ng/ml 46 21 0.045 32 23 0.652
 > 20 ng/ml 105 88 122 103
Virus infection HBV 108 84 0.523 119 106 0.406
HCV 14 11 11 8
HBV + HCV 9 3 11 4
none 20 11 13 8
Cirrrhosis absent 40 32 0.674 42 34 1.000
present 111 77 112 92
Child–pugh score Class A 113 83 0.884 130 103 0.630
Class B 38 26 24 23
Tumor number single 91 63 0.703 124 86 0.026
multiple 60 46 30 40
Maximal tumor size  ≤ 5 cm 69 39 0.126 102 56  < 0.001
 > 5 cm 82 70 52 70
Tumor encapsulation present 95 50 0.008 118 77 0.006
absent 56 59 36 49
Microvascular invasion absent 97 45  < 0.001 97 56 0.003
present 54 64 57 70
Tumor differentiation I-II 131 75 0.001 132 77  < 0.001
III-IV 20 34 22 49
TNM stage I-II 128 70  < 0.001 136 82  < 0.001
III 23 39 18 44