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. 2022 Sep 15;17:108. doi: 10.1186/s13020-022-00664-x

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Effect of tea on the liver of rats with hyperuricaemia. a Effects of teas on hepatic XOD activity and b Serum ALT in PO- and hypoxanthine-induced hyperuricaemia in rats. Data are given as the mean ± SD (n = 10). c Hematoxylin and eosin (H&E)-stained liver tissues. Scale bars, 100 μm. The yellow, black, green, orange and blue arrows indicate inflammatory infiltration, hepatocyte steatosis, hepatocyte death, fibroproliferative lesions around the central veins and capsular fibroproliferative lesions, respectively. d Immunohistochemical staining for F4/80 in liver tissue. Scale bars, 50 μm. e Quantification of the proportion of F4/80 -positive cells in the liver. ^#Represents a significant difference compared with the Con group, ^##P < 0.01; ^####P < 0.0001; *represents a significant difference compared with the Veh group, *P < 0.05, **P < 0.01, ***P < 0.001,****P < 0.0001