Skip to main content
. 2022 Sep 2;10:851087. doi: 10.3389/fcell.2022.851087

TABLE 2.

PROTACs designed against BCR-ABL [Structures taken from PROTAC-DB (http://cadd.zju.edu.cn/protacdb/)]

PROTAC Warhead Linker E3 ligand
Inline graphic SNIPER(ABL)-2 graphic file with name FCELL_fcell-2022-851087_wc_tfx2.jpg graphic file with name FCELL_fcell-2022-851087_wc_tfx3.jpg Inline graphic E3 ligase: cIAP1
Inline graphic SNIPER(ABL)-39 graphic file with name FCELL_fcell-2022-851087_wc_tfx6.jpg graphic file with name FCELL_fcell-2022-851087_wc_tfx7.jpg Inline graphic E3 ligase: cIAP1
Inline graphic SNIPER(ABL)-21 graphic file with name FCELL_fcell-2022-851087_wc_tfx10.jpg graphic file with name FCELL_fcell-2022-851087_wc_tfx11.jpg Inline graphic E3 ligase: cIAP1
Inline graphic SNIPER(ABL)-62 graphic file with name FCELL_fcell-2022-851087_wc_tfx14.jpg graphic file with name FCELL_fcell-2022-851087_wc_tfx15.jpg Inline graphic E3 ligase: cIAP1
Inline graphic GMB-475 graphic file with name FCELL_fcell-2022-851087_wc_tfx18.jpg graphic file with name FCELL_fcell-2022-851087_wc_tfx19.jpg Inline graphic E3 ligase: VHL
Inline graphic SIAIS178 graphic file with name FCELL_fcell-2022-851087_wc_tfx22.jpg graphic file with name FCELL_fcell-2022-851087_wc_tfx23.jpg Inline graphic E3 ligase: VHL