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. 2022 Sep 2;15:976349. doi: 10.3389/fnmol.2022.976349

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Copyright © 2022 Tsuneoka, Atsumi, Makanae, Yashiro and Funato.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Overview of the LED illuminator, TiYO^TM. (A) Frontal view and (B) back view of the LED illuminator. (C) Lateral illustration of the LED illuminator. Two high-power LEDs (more than 3,000 lumens/single LED) are placed in one column, and the LEDs are arrayed as 2 × 6. LED circuit boards are mounted on a large heat sink (12 × 24 × 12 cm). On the upper side of the sample, a mirror with a heat sink (3 × 24 × 12 cm) is placed. Two heat sinks are cooled by cooling fans. The airflow shown by the blue arrow also removes heat from the buffer solution in the acrylic container. (D) Inside view of the LED illuminator. (E) Temperature change of the buffer solution inside the acrylic container according to the duration of photoirradiation. (F) Spectrum of the LED used in this study.