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. 2022 Aug 23;13:981917. doi: 10.3389/fimmu.2022.981917

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Copyright © 2022 Fu, Liu, Chen, Hooft, Øverland, Cai, Han, Zhu, Yang, Jin and Xie

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The TNBS enhanced the respiratory of mitochondria in liver. (A) Representative effects of TNBS on mitochondrial function. The oxygen flux at different respiration states is obtained by introducing specific substrates and inhibitors to the samples. Red line, oxygen consumption in response to the application of substrates for complex I (CI) and II (CII) with 125 μL/kg SS. Green line, with 125 μL/kg TNBS. (B) Summarized data for oxygen consumption in the liver as measured via Oxygraph-2k high-resolution respirometry. P value was calculated by Student’s t tests. All data are expressed as mean ± S.E.M. (N = 7). *P< 0.05, compared with PBS groups.