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. 2022 Aug 11;16:946879. doi: 10.3389/fnins.2022.946879

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Copyright © 2022 Zhou, Chen, Yu, Pan, Fang, Li, Cui, Yao and Lu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Overall analyses of the effects of metformin on tissue damage in lesion area. (A,B) Tissue preservation area ratio, number of survival motor neuron meta-analysis in lesion area and the effect sizes line chart.