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. 2022 Aug 11;16:946879. doi: 10.3389/fnins.2022.946879

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Copyright © 2022 Zhou, Chen, Yu, Pan, Fang, Li, Cui, Yao and Lu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The SUCRA value and probabilities of each treatment doses. (A) SUCRA value ranking of different administration doses according to data on 28th day. (B) Histogram of ranking probability of each treatment dose according to data on 28th day. (C) SUCRA value ranking of different administration doses according to data on 21th day. (D) Histogram of ranking probability of each treatment dose according to data on 21th day. a, control; b, 10 mg/kg metformin; c, 50 mg/kg metformin; d, 100 mg/kg metformin, e, 200 mg/kg metformin; f, 320 mg/kg metformin.