Table 2.
Evaluation of the benefits of combined extracts in mice by the open field test (OFT) and the forced swimming test (FST).
| Group (n = 8) a,b | Positive control | Control | Low dose | Medium dose | High dose | |
|---|---|---|---|---|---|---|
| Open field test | Frequency | 11.38 ± 1.16 | 9.50 ± 1.34 | 10.25 ± 0.82 | 10.75 ± 1.08 | 11.25 ± 0.56 |
| Duration time (sec) | 17.63 ± 1.13 | 12.13 ± 1.20 | 14.75 ± 1.69 | 16.63 ± 1.85 | 17.25 ± 1.45 | |
| Distance traveled (mm) | 691 ± 110.51 | 371.71 ± 66.74 | 447.05 ± 56.74 | 627.85 ± 72.00 | 663.38 ± 88.65 | |
| Velocity (mm/s) | 29.85 ± 4.15 | 18.18 ± 1.93 | 18.84 ± 1.36 | 19.25 ± 2.12 | 20.20 ± 3.14 | |
| Forced swimming test | Immobility time (sec) | 207.58 ± 12.32 | 254.83 ± 13.81 | 228.35 ± 12.41 | 216.45 ± 8.17 | 210.51 ± 10.89 |
Data are expressed as the mean ± S.E.M. (n = 8) and analyzed by one-way ANOVA.
Data points were not significantly different (p > 0.05) from each other according to ANOVA. Positive control: CORT (40 mg/kg/day) + Fluoxetine (20 mg/kg/day). Control: CORT (40 mg/kg/day). Low dose: CORT (40 mg/kg/day) + combined extracts of chlorella and lion's mane mushroom (contains 0.1 mL chlorella extract concentrate + 6 mg lion's mane mushroom extract concentrate). Medium dose: CORT (40 mg/kg/day) + combined extracts of chlorella and lion's mane mushroom (contains 0.2 mL chlorella extract concentrate + 12 mg lion's mane mushroom extract concentrate). High dose: CORT (40 mg/kg/day) + combined extracts of chlorella and lion's mane mushroom (contains 0.4 mL chlorella extract concentrate + 24 mg lion's mane mushroom extract concentrate).