Table 4.
Effects of combined extracts on the levels of factors correlated to the central nervous system in brain of mice.
| Group (n = 8) a,b | Positive control | Control | Low dose | Medium dose | High dose |
|---|---|---|---|---|---|
| Serotonin (%) | 92.50 ± 4.88 | 100.00 ± 8.59 | 96.24 ± 6.97 | 94.02 ± 6.70 | 95.64 ± 10.08 |
| Dopamine (%) | 94.45 ± 10.90 | 100.00 ± 6.76 | 98.55 ± 5.75 | 98.53 ± 10.34 | 99.42 ± 6.86 |
| BDNF (%) | 141.97 ± 8.73 | 100.00 ± 9.40 | 114.09 ± 12.68 | 118.84 ± 5.51 | 122.81 ± 8.56 |
Data are expressed as the mean ± S.E.M. (n = 8) and analyzed by one-way ANOVA.
Data points were not significantly different (p > 0.05) from each other according to ANOVA. Positive control: CORT (40 mg/kg/day) + Fluoxetine (20 mg/kg/day). Control: CORT (40 mg/kg/day). Low dose: CORT (40 mg/kg/day) + combined extracts of chlorella and lion's mane mushroom (contains 0.1 mL chlorella extract concentrate + 6 mg lion's mane mushroom extract concentrate). Medium dose: CORT (40 mg/kg/day) + combined extracts of chlorella and lion's mane mushroom (contains 0.2 mL chlorella extract concentrate + 12 mg lion's mane mushroom extract concentrate). High dose: CORT (40 mg/kg/day) + combined extracts of chlorella and lion's mane mushroom (contains 0.4 mL chlorella extract concentrate + 24 mg lion's mane mushroom extract concentrate).