Table II.

Target levels of LDL cholesterol and non-HDL cholesterol in patients with metabolic syndrome

	High CV risk	Very high CV risk
Factors associated with a given CV risk category	High risk as per SCORE2 or SCORE2-OP Chronic kidney disease (eGFR 30–60 ml/min/1.73 m2)	Very high risk as per SCORE2 or SCORE2-OP Atherosclerotic cardiovascular disease Diabetes mellitus Chronic kidney disease (eGFR < 30 ml/min/1.73 m2)
Target LDL cholesterol level	< 70 mg/dl (1.8 mmol/l) and reduction by ≥ 50% compared to baseline	< 55 mg/dl (1.4 mmol/l) and reduction by ≥ 50% compared to baseline
Target non-HDL cholesterol level	< 100 mg/dl (2.6 mmol/l)	< 85 mg/dl (2.2 mmol/l)

CV – cardiovascular, eGFR – estimated glomerular filtration rate, HDL – high-density lipoprotein, LDL – low-density lipoprotein.