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. 2022 Oct;28(10):1298–1314. doi: 10.1261/rna.079170.122

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© 2022 Cascarina and Ross; Published by Cold Spring Harbor Laboratory Press for the RNA Society

This article, published in RNA, is available under a Creative Commons License (Attribution 4.0 International), as described at http://creativecommons.org/licenses/by/4.0/.

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FIGURE 2. — Sequence and PTM characteristics among RBP and non-RBP SR/SR-related proteins. (A) Percent composition within the RS domains of known SR/SR-related proteins, stratified into categories. “Known” SR/SR-related RBPs are from Long and Caceres (2009), “New” SR-related RBPs are the 35 proteins outlined in red in Figure 1C, and “Non-RBP” represents the 48 non-RBP SR-related proteins not found in the Long and Caceres data set and not classified as RBPs (see Fig. 1C). Composition analyses for all amino acids within RS domains can be found in Supplemental Figure S4. (B) Lengths of RS domains in known SR/SR-related RBPs, new SR-related RBPs, and SR-related non-RBPs. (C) Total number of SR and RS dipeptide sites and phosphorylation sites in RS domains of known SR/SR-related RBPs, new SR-related RBPs, and SR-related non-RBPs. (D) Density of SR/RS dipeptide sites and phosphorylation sites in known SR/SR-related RBPs, new SR-related RBPs, and SR-related non-RBPs.