Additional Table 2.

Univariate analysis of possible outcome predictors for treatment effects at four time points in ozone group

Predictor	Pre-treatment					3 mon					6 mon					1 yr
	Effective	Ineffective	OR	95% CI	P-value	Effective	Ineffective	OR	95% CI	P-value	Effective	Ineffective	OR	95% CI	P-value	Effective	Ineffective	OR	95% CI	P-value
Age (yr)			1.4	0.3	0.5			0.8	0.2	0.8			0.7	0.2	0.5			0.2	0.0	0.0
< 65	5	15	67	61-	91	4	16	75	11-	54	8	12	18	23-	79	7	13	27	66-	14*
≥65	5	22		5.9 63		6	21		3.629		13	14		2.315		19	8		0.780
Gender			0.5	0.1	0.4			0.5	0.1	0.4			2.2	0.6	0.1			0.6	0.2	0.4
Male	4	20	67	37-	30	4	20	67	37-	30	13	11	16	84-	81	12	12	43	92-	54
	6	17		2.2		6	17		2.3		8	15		7.1		14	9		2.0
Female				46					46					77					47
Disease			0.0	0.3	0.7			0.7	0.1	0.7			0.8	0.2	0.7			0.6	0.1	0.4
course			49	08-	37	5	21	60	88-	03	11	15	07	54-	16	13	13	15	91-	14
(yr)				5.2		5	16		3.0		10	11		2.5		13	8		1.9
< 1	6	20		79					89					66					81
≥1	4	17
Diabete			2.8	0.4	0.2			2.8	0.4	0.2			0.2	0.0	0.2			1.2	0.1	0.8
s	2	3	33	04-	79	2	3	33	04-	79	1	4	75	28-	40	3	2	39	87-	24
With	8	34		19.873		8	34		19.873		20	22		2.671		23	19		8.199
Without
Hyperte			0.9	0.5	0.3			1.2	0.2	0.7			0.8	0.2	0.7			1.2	0.3	0.7
nsion	5	12	60	05-	05	4	13	31	93-	76	7	10	00	40-	16	10	7	50	75-	16
With	5	25		8.601		6	24		5.163		14	16		2.664		16	14		4.163
Without
Treatm			0.4	0.0	0.2			1.4	0.2	0.6			0.7	0.2	0.6			0.8	0.2	0.8
ent			14	93-	37			81	68-	51			50	01	68			48	25-	08
number	6	29		1.8		8	27		8.1		15	20		2.7		19	16		3.1
<10	4	8		32		2	10		99		6	6		93		7	5		96
≥10

Note: CI: Confidence interval; OR: odd ratio.