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. 2022 Jun 30;11(6):2648–2655. doi: 10.4103/jfmpc.jfmpc_1987_21

Table 2.

Primary and secondary outcomes including in our meta-analysis

Study/Trial name Treatment /Control group PFS of 18 months since first dose of Daratumumab ORR* VGPR* CR* PR* MR*
Dimopoulo s et al./CANDOR Trial Treatment group 57 (18.3%) 263 (84.3%) 216 (69%) 89 (28.5%) 55 (17.6%) 23 (7.4%)
Control group 13 (8%) 115 (74.6%) 75 (49%) 16 (10.4%) 6 (4%) 22 (14.3%)
Spencer, et al./CASTOR trial Treatment group 188 (74%) 201 (80.1%) 149 (59.3%) 69 (27.4%) 52 (20.7%) 9 (3.6%)
Control group 24 (9.7%) 148 (59.9%) 68 (27.5%) 23 (9.3%) 80 (32.4%) 20 (8.1%)
Dimopoulo s, et al./POLLUX Trial Treatment group 203 (71%) 261 (91.2%) 221 (77.2%) 144 (50.3%) 40 (14%) 5 (1.7%)
Control group 127 (45%) 211 (74.5%) 132 (46.6%) 58 (20.5%) 79 (28%) 26 (9.2%)

*PFS: Progression free span, ORR=overall response rate, VGPR=Very good partial response, CR=Complete response, PR=Partial response, MR=Minimal Response