Table 2. Genotype distribution in professional athletes, elite endurance athletes, professional football players and non-athletes of iron metabolism and energy efficiency polymorphisms.
Symbol | Gene | Polymorphism | dbSNP | Genotype Score | Professional athletes | Elite endurance athletes | Professional football players | Elite endurance athletes vs. Professional football players p-value | non-athletes | Professional athletes vs. non-athletes p-value | Elite endurance athletes vs. non-athletes p-value | Professional football players vs. non-athletes p-value |
---|---|---|---|---|---|---|---|---|---|---|---|---|
HFE | Homeostatic Iron Regulator | c.187C>G | rs1799945 | 2 = GG | 16 (5.8%) | 8 (5.0%) | 8 (6.1%) | 0.001 | 0 (0.0%) | 0.001 | <0.001 | 0.013 |
1 = GC | 115 (39.0%) | 78 (48.8%) | 37 (28.0%) | 43 (26.8%) | ||||||||
0 = CC | 161 (55.2%) | 74 (46.2%) | 87 (65.9%) | 117 (73.2%) | ||||||||
HFE | Homeostatic Iron Regulator | c.845G>A | rs1800562 | 2 = AA | 1 (0.3%) | 0 (0.0%) | 1 (0.8%) | 0.449 | 0 (0.0%) | 0.621 | 0.998 | 0.404 |
1 = GA | 16 (5.5%) | 10 (6.3%) | 6 (4.5%) | 10 (6.3%) | ||||||||
0 = GG | 275 (94.2%) | 150 (93.7%) | 125 (94.7%) | 150 (93.7%) | ||||||||
AMPD1 | Adenosine monophosphate deaminase 1 | c.34C>T | rs17602729 | 2 = CC | 233 (79.8%) | 128 (80.0%) | 105 (79.6%) | 0.291 | 99 (62.1%) | 0.006 | 0.010 | 0.014 |
1 = CT | 57 (19.5%) | 32 (20.0%) | 25 (18.9%) | 60 (37.4%) | ||||||||
0 = TT | 2 (0.7%) | 0 (0.0%) | 2 (1.5%) | 1 (0.5%) | ||||||||
PGC1a | Peroxisome proliferator activated receptor coactivator | c.1444 G>A | rs8192678 | 2 = GG | 192 (65.7%) | 105 (65.6%) | 87 (65.9%) | 0.347 | 88 (54.8%) | 0.232 | 0.523 | 0.119 |
1 = GA | 91 (31.1%) | 53 (33.1%) | 38 (28.8%) | 63 (39.7%) | ||||||||
0 = AA | 9 (3.2%) | 2 (1.3%) | 7 (5.3%) | 9 (5.5%) |