Table 3. Genotype distribution in professional athletes, elite endurance athletes, professional football players and non-athletes of cardiorespiratory fitness polymorphisms.
| Symbol | Gene | Polymorphism | dbSNP | Genotype Score | Professional athletes | Elite endurance athletes | Professional football players | Elite endurance athletes vs. Professional football players p-value | non-athletes | Professional athletes vs. non-athletes p-value | Elite endurance athletes vs. non-athletes p-value | Professional football players vs. non-athletes p-value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACE | Angiotensin I-converting enzyme | Alu 287bp (I/D) | rs4340 | 2 = II | 38 (13.0%) | 25 (15.6%) | 13 (9.8%) | 0.175 | 16 (10.1%) | 0.034 | 0.011 | 0.276 |
| 1 = ID | 114 (39.1%) | 56 (35.0%) | 58 (43.9%) | 82 (51.2%) | ||||||||
| 0 = DD | 140 (47.9%) | 79 (49.4%) | 61 (46.3%) | 62 (38.7%) | ||||||||
| NOS3 | Nitric Oxide Synthase 3 | c.-786T>C | rs2070744 | 2 = TT | 130 (44.6%) | 82 (51.2%) | 48 (36.4%) | 0.037 | 48 (30.3%) | 0.044 | 0.005 | 0.506 |
| 1 = TC | 114 (39.0%) | 54 (33.8%) | 60 (45.5%) | 67 (41.8%) | ||||||||
| 0 = CC | 48 (16.4%) | 24 (15.0%) | 24 (18.1%) | 45 (27.9%) | ||||||||
| NOS3 | Nitric Oxide Synthase 3 | c.894G>T | rs1799983 | 2 = GG | 137 (46.9%) | 71 (44.4%) | 66 (50.0%) | 0.406 | 63 (39.1%) | 0.227 | 0.329 | 0.201 |
| 1 = GT | 136 (46.6%) | 80 (50.0%) | 56 (42.4%) | 81 (50.8%) | ||||||||
| 0 = TT | 19 (6.5%) | 9 (5.6%) | 10 (7.6%) | 16 (10.1%) | ||||||||
| ADRA2A | Adrenoceptor α-2a | c.-1291C>G | rs1800544 | 2 = CC | 135 (46.2%) | 71 (44.2%) | 64 (48.5%) | 0.759 | 90 (56.4%) | 0.010 | 0.008 | 0.033 |
| 1 = GC | 123 (42.3%) | 69 (43.5%) | 54 (40.9%) | 66 (41.3%) | ||||||||
| 0 = GG | 34 (11.5%) | 20 (12.3%) | 14 (10.6%) | 4 (2.3%) | ||||||||
| ADRB2 | Adrenergic receptor β-2 | c.46A>G | rs1042713 | 2 = AA | 33 (11.3%) | 15 (9.4%) | 18 (13.6%) | 0.034 | 14 (9.1%) | 0.607 | 0.751 | 0.119 |
| 1 = GA | 146 (50.0%) | 91 (56.9%) | 55 (41.7%) | 87 (54.4%) | ||||||||
| 0 = GG | 113 (38.7%) | 54 (33.7%) | 59 (44.7%) | 59 (36.5%) | ||||||||
| ADRB2 | Adrenergic receptor β-2 | c.79C>G | rs1042714 | 2 = CC | 92 (31.5%) | 43 (26.9%) | 49 (37.1%) | 0.056 | 26 (16.0%) | <0.001 | <0.001 | <0.001 |
| 1 = GC | 164 (56.2%) | 100 (62.5%) | 64 (48.5%) | 77 (48.3%) | ||||||||
| 0 = GG | 36 (12.3%) | 17 (10.6%) | 19 (14.4%) | 57 (35.7%) | ||||||||
| BDKRB2 | Bradykinin Receptor β2 | +9 pb/-9 pb | rs5810761 | 2 = -9/-9 | 74 (25.3%) | 33 (20.6%) | 41 (31.1%) | <0.001 | 38 (23.8%) | 0.153 | 0.003 | 0.373 |
| 1 = -9/+9 | 129 (44.2%) | 61 (38.1%) | 68 (51.5%) | 84 (52.4%) | ||||||||
| 0 = +9/+9 | 89 (30.5%) | 66 (41.3%) | 23 (17.4%) | 38 (23.8%) |