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. 2022 Sep 16;17(9):e0274520. doi: 10.1371/journal.pone.0274520

Table 2. Characteristics of the patients and results of the evaluation measures according to the severity profile.

TOTAL p ICU P1 WARD P2 No Admission P3
N 178 91 (51.1%) 60 (33.7%) 27 (15.2%)
Male (n / %) 105 (58.9%) <0.001 65 (71.4%) 0.008 30 (50%) 0.145 9 (33.3%) <0.001
Age 59.6±11.6 <0.001 63.3 ± 9.9 0.025 58.5 ± 11.7 0.010 50.9±12.5 < 0.001
Comorbidities 152 (85,4%) 0.609 80 (87.9%) 0.430 50 (83.3%) 0.833 22 (81.5%) 0.406
Barthel Index 96.5±7.7 0.002 94.5±9.6 0.012 98.2±4.5 0.896 99.3±3.8 0.014
Cognitive impairment (Pfeiffer) n/% 11 (6,2%) 0.121 7 (7.8%) 0.078 1 (1.7%) 0.064 3 (11.1%) 0.597
mMRC dyspnoea (n /%) 134 (75.3%) 0.682 66 (72.5%) 0.418 47 (78.3%) 0.954 21(77.8%) 0.581
HAD anxiety n/% 56 (31.5%) 0.001 17 (18.7%) <0.001 28 (46.7%) 0.606 11(40.7%) 0.023
HAD depression n/% 42 (23.6%) 0.096 16 (17.6%) 0.185 16 (26.7%) 0.333 10 (37%) 0.04
SF36 PCS 36.4±9.4 0.254 36.9±9.5 0.99 37±9.1 0.3 33.4±9.6 0.308
SF 36 MCS 44.6±11.8 0.007 47.7±10.9 0.008 41±11.1 0.658 43.6±13.8 0.397
mMRC strength 57.6±3.9 <0.001 56.3±4.5 <0.001 58.8±2.5 0.891 59.3±1.1 0.002
SPPB 9.6±2.6 0.155 9.3±2.8 0.269 10±2.3 0.954 10.2±2.1 0.335
Dynamometry impairment n/% 146 (82.5%) 0.001 83 (92.2%) <0.001 41 (68%) 0.193 22 (81.5%) 0.129
P6MM (meters) 435.9±138 0.001 403.8±140.8 0.120 450.1±138.9 0.145 512.1±85.2 0.002
Desaturation (SpO 2 ) (n) 26 (14.6%) 0.006 18 (69.2%) 0.298 8 (30.8%) 0.012 0 0.001
PImax (cmH 2 O) 79.1±26.6 0.279 82.1±28.2 0.51 76.9±27.1 0.89 73.9±18.1 0.38
PEmax (cm H 2 O) 101.8±27.3 0.881 102.5±24.3 0.9 100.3±34.9 0.93 102.7±16.1 0.99

ICU: patients admitted to the intensive care unit, general ward, and not admitted. mMRC: Modified Medical Research Council scale; HAD: hospital anxiety and depression questionnaire SF36: quality of life questionnaire; 6MWT: 6-minute walk test; SpO2: oxyhemoglobin saturation; PImax: maximum inspiratory pressure; PEmax: maximum expiratory pressure. p = comparison between the three groups; p1 = comparison between ICU-ward; p2 = comparison between ward—no admission; p3 = comparison between ICU-no admission.