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. 2022 Sep 13;11(1):2120676. doi: 10.1080/2162402X.2022.2120676

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© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Combination of targeted therapy and immunotherapy with or without chemotherapy in different solids tumors. Heatmap represents recent or ongoing clinical trials combining targeted therapy (classified in function of target pathway), immunotherapy (anti-PD-(l)1 or anti-CTLA-4 or both) and chemotherapy. This non-exhaustive list was done in July 2022 (from ClinicalTrials.gov) within the main cancers presented in this review. NSCLC: non small cell lung carcinoma, SCLC: small cell lung carcinoma, BRCA: breast carcinoma, CCR: colorectal cancer, HCC: hepatocellular carcinoma, PANC: pancreatic cancer, MEL: melanoma. Color code is specified bellow the heat map.