Table 3. TRIM25-R54P interactors during viral infection.
Interactors pulled down in both independent experiments shown here; proteins also enriched in TRIM25-WT co-IP in both independent experiments are italicized and bolded. Fold change = FC. In EXP #2, the “i” prefacing log2FC and Pvalue refers to how missing data values were imputed.
| Protein | EXP #1 log2FC | EXP #2 ilog2FC | EXP #1 -log10Pvalue | EXP #2 -log10iPvalue |
|---|---|---|---|---|
| TRIM25 | 13.82 | 6.87 | 5.83 | 1.28 |
| G3BP2 | 9.50 | 7.66 | 4.71 | 1.40 |
| G3BP1 | 5.25 | 2.51 | 4.58 | 1.92 |
| NME1 | 4.81 | 3.43 | 2.84 | 1.40 |
| H1FX | 4.65 | 4.49 | 3.14 | 1.46 |
| UPF1 | 4.64 | 5.24 | 3.44 | 1.94 |
| ZC3HAV1 | 4.47 | 2.77 | 2.77 | 1.42 |
| RPL8 | 4.26 | 2.98 | 2.36 | 1.80 |
| PABPC4 | 4.25 | 2.67 | 3.42 | 1.42 |
| PABPC1 | 4.24 | 3.54 | 2.44 | 1.44 |
| HP1BP3 | 4.00 | 4.09 | 3.44 | 1.50 |
| LARP1 | 3.93 | 4.59 | 4.32 | 1.61 |
| DDX50 | 3.74 | 4.14 | 2.08 | 1.47 |
| RPL21 | 3.40 | 3.45 | 1.50 | 1.44 |
| RPL29 | 3.38 | 2.53 | 2.48 | 2.06 |
| HSPA9 | 3.28 | 2.04 | 4.15 | 2.05 |
| ZCCHC3 | 3.23 | 4.49 | 1.95 | 1.54 |
| RPS3A | 3.18 | 1.53 | 1.36 | 1.38 |
| GLYR1 | 3.01 | 2.59 | 1.43 | 1.59 |
| YBX1 | 2.61 | 1.73 | 1.44 | 1.44 |
| GNL3L | 2.47 | 5.28 | 2.35 | 1.58 |
| RPL19 | 2.44 | 2.90 | 2.39 | 1.75 |
| MRPS26 | 1.98 | 1.90 | 1.49 | 1.31 |
| MRPS9 | 1.58 | 2.56 | 2.02 | 1.38 |