Table 2.

Statistical evaluation of biomarkers for previous infection prediction.

Analyte	AUC	S.E.	P value	Confidence interval (CI)	Cut-off value	Sensitivity	Specificity
Negative factors
MCP-1 (pg/mL)	0.966	0.014	< 0.001	0.938-0.995	272. 76	0.966	0.870
CRP (mg/L)	0.725	0.053	< 0.001	0.621-0.828	1.11	0.793	0.739
Factor D (μg/mL)	0.914	0.039	< 0.001	0.838-0.990	1.26	0.862	0.902
PAI-1 (ng/mL)	0.885	0.050	< 0.001	0.787-0.984	62.52	0.862	0.946
Positive factors
IL-6 (pg/mL)	0.890	0.037	< 0.001	0.818-0.963	10.67	0.793	0.826
IL-10 (pg/mL)	0.852	0.046	< 0.001	0.761-0.942	24.50	0.862	0.761
Leptin (ng/mL)	0.677	0.056	0.004	0.567-0.786	28.77	0.690	0.620
Adiponectin (μg/mL)	0.876	0.049	< 0.001	0.779-0.972	5.26	0.793	0.978