Figure 1.

Morphological growth of the mouse hind limb

(A) Three mouse embryos at different developmental stages: E10:09, E11:05, and E12:02.

(B) Graphical illustration of a smooth trajectory taking into account all the different characteristics of the dataset.

(C) Two-dimensional interpolation of mouse limb from E10:06 to E12:06 at 6-h intervals.

(D) Alignment of three embryos at the same developmental stage according to their right hind limbs shown with transparency (left) and as surface in solid color (right). The red line represents the output of the staging system (Musy et al., 2018).

(E) Dataset of mouse right hind limbs used in this study ordered according to their developmental stage from E10:09 to E12:02.