Table 1.
Variables | ALS patients (n = 32) | Controls (n = 32) |
Male, n | 19 | 14 |
Age at sample collection, mean (SD) | 54.7 (10.2) | 38.6 (10.0) |
Age of onset, mean (SD) Site of onset, n | 53.5 (10.2) | – |
Bulbar | 10 | – |
Limb | 22 | – |
Disease duration (months), median (IQR) | 11.5 (11.0) | – |
ALSFRS-R score, median (IQR) | 37 (11) | – |
DALSFRS-R, median (IQR) King's stage, n | 0.9 (1.0) | – |
2 | 14 | – |
3 | 6 | – |
4 | 12 | – |
ΔALSFRS-R: (48 - ALSFRS-R at baseline)/duration from symptom onset to baseline clinical diagnosis in months. ALS: Amyotrophic lateral sclerosis; ALSFRS-R: Revised ALS Functional Rating Scale; IQR: Interquartile range; SD: Standard deviation.