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OS in NSCLC patients with (A) liver metastasis; (B) contralateral lung metastasis; (C) adrenal metastasis; (D) bone metastasis; (E) pleural metastasis; (F) different metastatic burden; (G) brain metastasis; (H) different metastatic sites treated with first-line ICIs monotherapy. ICIs: Immune checkpoint inhibitors; NSCLC: Non-small-cell lung cancer; OS: Overall survival; mOS: Median OS.
